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主题:【讨论】长新冠主要是心理作用?请大家讨论、批判 -- 学步桥

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家园 【讨论】长新冠主要是心理作用?请大家讨论、批判

之前不敢贴,怕被骂给躺平找依据。现在出了20条,或许是时候可以讨论了。大家要骂骂作者或者德国腐朽的资本主义制度,别骂我哟。

Post-COVID-19 Syndrome is Rarely Associated with Damage of the Nervous System: Findings from a Prospective Observational Cohort Study in 171 Patient

链接里是原文。我英语水平一般,我的理解是,作者找了一百来个满足WHO定义的长新冠病人,不计成本,把神经病学的检查手段用了个够(神经血管、电生理和血液分析。 部分患者进行了磁共振成像和腰椎穿刺检查。 )然后结论是绝大部分人没有器质性疾病。我水平一般,请大家发表自己的看法,大概率我有读的不准确的地方。

下面是摘要。

Abstract

Introduction

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can affect multiple organs. Reports of persistent or newly emergent symptoms, including those related to the nervous system, have increased over the course of the pandemic, leading to the introduction of post-COVID-19 syndrome. However, this novel syndrome is still ill-defined and structured objectification of complaints is scarce. Therefore, we performed a prospective observational cohort study to better define and validate subjective neurological disturbances in patients with post-COVID-19 syndrome.

Methods

A total of 171 patients fulfilling the post-COVID-19 WHO Delphi consensus criteria underwent a comprehensive neurological diagnostic work-up including neurovascular, electrophysiological, and blood analysis. In addition, magnetic resonance imaging (MRI) and lumbar puncture were conducted in subgroups of patients. Furthermore, patients underwent neuropsychological, psychosomatic, and fatigue assessment.

Results

Patients were predominantly female, middle-aged, and had incurred mostly mild-to-moderate acute COVID-19. The most frequent post-COVID-19 complaints included fatigue, difficulties in concentration, and memory deficits. In most patients (85.8%), in-depth neurological assessment yielded no pathological findings. In97.7% of the cases, either no diagnosis other than post COVID-19 syndrome, or no diagnosis likely related to preceding acute COVID-19 could be established. Sensory or motor complaints were more often associated with a neurological diagnosis other than post-COVID-19 syndrome. Previous psychiatric conditions were identified as a risk factor for developing post-COVID-19 syndrome. We found high somatization scores in our patient group that correlated with cognitive deficits and the extent of fatigue.

Conclusions

Albeit frequently reported by patients, objectifiable affection of the nervous system is rare in post-COVID-19 syndrome. Instead, elevated levels of somatization point towards a pathogenesis potentially involving psychosomatic factors. However, thorough neurological assessment is important in this patient group in order to not miss neurological diseases other than post-COVID-19.

Key Summary Points

Why carry out this study?

To validate subjective neurological complaints in patients with post-COVID-19 by applying a comprehensive neuro-psychiatric diagnostic workup.

What was learned from the study?

The nervous system is rarely affected in patients with post-COVID-19 syndrome.

Psychosomatic factors probably contribute to the pathogenesis of post-COVID-19 syndrome.

Patients presenting with post-COVID-19 should be thoroughly assessed in order to not miss other diagnoses.

另外,作者是德国的。据说德国请病假医保给付工资,不知道是不是真的。如果是,大概能解释一部分。请在德国的网友证实或者证伪。

通宝推:大爆炸,八段锦,普鲁托,方平,燕人,
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