主题：【原创】自闭症 Autism-送给中间派的您 -- 虽远必诛

主要争端是针对MMR (measles, mumps, rubella) 麻疹，风疹，腮腺炎三联免疫的。

在1998年2月Andrew Wakefield和其他12个医生在著名期刊the Lancet发表了一篇针对12个自闭症儿童的回顾性报告，提出MMR导致自闭症的理论。

但是此后很多的证据证明这个理论是错误的，（这种情况是经常出现的，孤证不成立，要能被重复），最新的Cochrane Reviews 也彻底否认了MMR同自闭症间的关系。

但是Andrew Wakefield获得了极大的所谓民间声誉

事情反过来说更加清楚一些，并不是Andrew Wakefield 自己要做科研，反而是那十二个患者的家属找到了他。

在the General Medical Council GMC 2007对他医疗失误的指控听证会上，指控的能容包括：

* He was being paid to conduct the study by solicitors representing parents who believed their children had been harmed by MMR, and failed to disclose this in his IRB.

* He ordered investigations "without the requisite paediatric qualifications".

* Acting "dishonestly and irresponsibly" in failing to disclose how patients were recruited for the study, and that some were paid to take part.

* Performing colonoscopies, colon biopsies and lumbar punctures ("spinal taps") on his research subjects without proper approval and contrary to the children's clinical interests, when these diagnostic tests were not indicated by the children's symptoms or medical history.

* Conducting the study on a basis which was not approved by the hospital's ethics committee.

* Purchasing blood samples - for 5 each - from children present at his son's birthday party, as described by Wakefield himself in a videotaped public conference.

实际上是非常清楚的，后来还有对实验数据修改的指控。

另外一个是Thimerosal一种含汞的疫苗防腐剂，现在已经停止使用了。

现在没有明显的证据能证明疫苗同自闭症的关系，社会明星不等于学术明星，国内外都一样。

至于说自闭症提高，很大程度上扩大的诊断范围的原因。另外就是社会认知程度的提高。本身自闭症就没有非常清楚的诊断，很多都是边界性。