五千年(敝帚自珍)

主题:纯技术贴:依照现有的资料,中医到底能治好什么病?请您讨论 -- 想象残酷

共:💬1054 🌺3045 🌵161
全看分页树展 · 主题 跟帖
家园 前面那段讨论麻杏石甘汤免疫调节机制的部分被华丽地无视了

你不做裁缝还真可惜了。

To our knowledge, this is the first registered randomized,

controlled trial to investigate the efficacy and safety of oseltamivir,TCM, and no treatment in H1N1 influenza A. We

found that resolution of fever was faster with maxingshigan–yinqiaosan than no intervention, but the improvement in symptoms was not significantly more rapid. Compared with active treatments, the reduction in median time to fever resolution between oseltamivir plus maxingshigan–yinqiaosan and oseltamivir (20.0 hours [CI, 17.0 to 24.0 hours] vs. 16.0 hours [CI, 14.0 to 17.0]) was only 19% (CI, 34% to 0.3%); this reached borderline statistical significance, but the difference was less than the margin of 12 hours. Therefore, with regard to clinical implication, we could not conclude that maxingshigan–yinqiaosan was superior to oseltamivir. We did not find evidence for differences in reductions in viral shedding; however, viral outcomes were available only for a subgroup of patients who had fewer symptoms and longer time from illness onset to randomization.

The mechanism of TCM in the treatment of influenza

is complex. Zhao and colleagues (21) found that maxingshigan regulated the percentage of T-cell subpopulation in mice exposed to influenza virus A. Investigators also found that maxingshigan had inhibitory effects on influenza virus A by directly killing the virus, interfering with virus adsorption, inhibiting virus proliferation, and protecting the cells from being infected with virus. Except in terms of inhibiting virus proliferation, maxingshigan performed much better than ribavirin (22, 23). During the outbreak of the severe acute respiratory syndrome in Hong Kong,Poon and associates (24) showed that 2 herbal formulas had immunomodulating effects. In their study of healthy volunteers, they found that the CD4–CD8 ratio of T lymphocytes was significantly increased after participants received Chinese herbal medicine for 14 days (24). Administration of Chinese herbs may have beneficial immunomodulatory effects for rapid recovery of viral infections.More studies are needed to clarify the mechanisms of TCM.

还有你摘的这段的前提也给你漏了:

Participants in our study were relatively young and

largely had very mild disease. They were admitted to hospitals

for quarantine purposes, not because of the severity

of the illness. Because disease was mild in these patients, we could not detect a difference in the rate of improvement of symptoms, except fever, in the intervention groups compared with control.

参与病毒检测对照组的年轻患者病情都比较轻微,所以只能检测到退烧的改善。

结合上下文就能知道,这个总结是指麻杏石甘汤合银翘散的疗效不劣于达菲,这是阳性对照实验,能得出不劣于就已经达到实验目的了。达菲的疗效的机制是直接抗病毒,中药并不是直接抗病毒。中药治甲流的机制需要更深的研究。

顺便说一句,达菲一盒300元一个疗程,麻杏石甘汤合银翘散汤剂的话一个疗程大概4到50元钱左右。难怪诋毁中医的人那么多。

全看分页树展 · 主题 跟帖


有趣有益,互惠互利;开阔视野,博采众长。
虚拟的网络,真实的人。天南地北客,相逢皆朋友

Copyright © cchere 西西河