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主题:【原创】在医学上什么是证据?送给无知的人们 -- 虽远必诛

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家园 大夫,你这样就有点不地道啦。

Cure和完全无效之间还有很多合理的等级。反对“完全无效”就表示确认“CURE”吗?看来你的逻辑比你的英语水平差远了!

你引用的那个文献没有具体提到他们如何进行的试验,但是我理解他们的困难是无法设置一个合乎科学要求的试验方法。

the lack of trials of low enough risk of bias, or using a placebo or a drug clearly identified as a control,

您英语好,何妨把那个摘要全文翻译一下,让大家看看,到底有没有证据表明中药对普通感冒完全无效?当然,其他河友出手我也不反对。我把全文附在后面。

Abstract

Background

Chinese medicinal herbs are frequently used to treat the common cold in China. Until now, their efficacy has not been systematically reviewed.

Objectives

To assess the effectiveness and safety of Chinese medicinal herbs for the common cold.

Search strategy

We searched the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2008, issue 2), which contains the Cochrane Acute Respiratory Infections Group's Specialised Register; MEDLINE (1966 to May 2008); EMBASE (1980 to May 2008); AMED (1985 to May 2008); the Chinese Biomedical Database (CBMdisc) (1978 to May 2008); and China National Knowledge Infrastructure (CNKI) (1994 to May 2008).

Selection criteria

Randomised controlled trials (RCTs) studying the efficacy of Chinese medicinal herb(s) for the treatment of the common cold.

Data collection and analysis

Four review authors telephoned the original trial authors of the RCTs identified by our searches to verify the randomisation procedure. Two review authors extracted and analysed data from trials which met the inclusion criteria.

Main results

We found17 studies involving 3212 patients. The methods of 15 studies were at high risk of bias. In only two studies was the risk of bias low. Trials used "positive drugs", of which the efficacy was not known, as controls. Different Chinese herbal preparations were tested in nearly all trials. In only one trial was a Chinese herbal preparation tested twice. In seven trials, six herbal preparations were found to be more effective at enhancing recovery than the control preparations. In the other 10 studies, seven herbal preparations were not shown to be significantly different from the control. One study did not describe the difference between the intervention and control groups.

Authors' conclusions

Chinese herbal medicines may shorten the symptomatic phase in patients with the common cold. However, the lack of trials of low enough risk of bias, or using a placebo or a drug clearly identified as a control, means that we are uncertain enough to be unable to recommend any kind of Chinese medicinal herbs for the common cold.

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