主题：【整理】黎阳：为肖传国说句公道话（一个海归的杯具） -- 迷途笨狼
家园 就学术而讨论，老肖的手术方法有争论 有效率有一些，实际上治愈率为零。还有就是美国人看他的手术在中国有效，让他在美国做了几个手术，由于效果不理想停了这个说法不准确。
可以看一下下面的ppt，老肖的方法有疗效，但是也有副作用，只能说有较大争议。这个ppt是今年的
通宝推：南京老萝卜,家园 谢谢老兄的slide。肖的理论在美国的结果，试着翻译一下 在密歇根州做的9例，
----有7例在12月后有排泄反射
----4例有膀胱功能的改善
----5例有肠功能改善
----7例在12月后还要用导尿管（现在还有4例）
----最后1/9的例子看不懂
----膀胱功能总体上有提高
----最后一句，失禁仍然是问题
嗯，可以看出有一定改善
slide16 给了个overall 的评价：
----所有病人都有暂时性的腿部变弱
----12个月生活质量评价 3个变好，5个维持，1个变差（foot-drop，不知道啥意思）
---- 7个人还想再试一把，哈哈，到只有到北京监狱医院去找肖医生了
Results – 9 patients with 3 yr F/U
7/9 demonstrate voiding reflex at 12 months
Now only 2/9 – down-regulation by brain?
4/9 report improvement in bladder function
5/9 report improvement in bowel function
7/9 still required catheters at 12 months
Now only 4/9 require catheters
Only 1/9 still on medication (anticholinergic)
Bladder compliance overall improved
Incontinence “remains a problem”
本帖一共被 2 帖 引用 (帖内工具实现)
家园 桑兰自己的话 “邓朴方、桑兰都曾经找过我，希望我帮他们做手术。” 我这还是第一次听说，我有找过肖传国？我凹凸了？.......我的一个姐姐在纽约去中医诊所看病，那医生和我那个姐姐炫耀“知道桑兰吗？她都是我给治的！”姐姐立马起身：“桑兰和我很熟！”...看来我也成了“羊头”了！通宝推：南京老萝卜,
家园 【整理】假学术同仁送上门了，方肘子快去打压 假学术同仁送上门了，方肘子快去打压
要是肖某的反射弧是假的，这些专业支持者无疑也不是真专家
这些家伙不顺带打倒，光盯着肖某，除了怀疑以为过去抄袭被举报因此报复，想不出更好的理由
31位国际学术同仁声援肖传国医生的公开信 [ ★果酱 ] 于:2010-09-30 18:23:58 主题帖
我先请教各位河友：
方舟子质疑肖传国的学术成果是属于学术打假还是学术争论？
学术打假和学术争论有什么区别？
是不是质疑某人的某项学术成果，就可以认为自己在学术打假？
此处下载原文PDF文档 [sci.rutgers.edu]
Open letter in support of Chuan-Guo Xiao, M.D. from the
International Academic Community
September 29, 2010
To all,
We have all had the pleasure of knowing Dr. Chuan-Guo Xiao for many years. He is an
internationally respected surgeon-scientist who has made major advances in the
development of neuroregeneration to restore voiding and bowel function. Dr. Xiao
performed groundbreaking animal research in the United States, demonstrating that a
motor nerve that innervates the leg can be used to reinnervate the bladder and
bowel. This reinnervation allows for development of a reflex to initiate bladder
function. The results of his studies were published in peer-reviewed journals and
other scientists have replicated Xiao’s findings confirming these results.
Dr. Xiao eventually took the courageous step of moving from animal research to
human studies and began performing the rerouting procedure on patients with spinal
cord injury and spina bifida in China. Neurogenic bladder is life threatening in China
due to a lack of both antimuscarinics and intermittent catheterization, and lessening
the complications of neurogenic bladder would be considered a lifesaving success.
Patients with neurogenic bladder and bowel suffer greatly and endure a host of issues
such as urinary retention, incontinence, recurrent infections, renal insufficiency,
fecal incontinence, constipation, and poor quality of life. For a procedure as
complicated as nerve rerouting requiring nerve regeneration, one cannot expect
normalization of bladder and bowel function to be the definition of success. What is
important is that the benefits outweigh the risks of the procedure.
Dr. Xiao published his clinical results in peer-reviewed journals and was twice
honored by the Jack Lapides Essay Contest, one of the most respected international
awards given to scientists who make major contributions to the field of neurourology.
In 2008, he was named the Kelm Hjalmas Memorial Lecturer from the International
Children’s Continence Society for his scientific achievements. Many of us have
traveled to China to examine patients treated by Dr. Xiao and/or have been trained
by him in the nerve rerouting surgery he invented. Dr. Xiao is a very skilled surgeon
who is passionate about patient care and works tirelessly to train physicians around
the world in performing his nerve rerouting procedure.
In the United States, an independent and very rigorous pilot research trial was
performed to test the safety and efficacy of this procedure. The one-year results
were recently published in the Journal of Urology. At the 12-month follow-up visit, a
cutaneous to bladder reflex was found in 7 of 9 spina bifida patients, confirming that
rerouting does occur. This finding by itself is remarkable and Dr. Xiao should be
commended. In addition, a number of patients demonstrated improvement in bladder
and bowel function, which has continued to improve with longer patient follow-up.
The 36-month results are currently being analyzed and will be reported in the near
future. The pilot data was supportive of Dr. Xiao’s procedure, and now an NIH
sponsored clinical trial is being conducted to further study lumbar to sacral nerve
rerouting in spina bifida patients. In addition, similar procedures have been done
worldwide, with Dr. Xiao helping to mentor the surgeons at each site.
The Chinese people and government should be proud of Dr. Xiao for his dedication to
his patients, his scientific achievements, and his willingness to train doctors around
the world how to perform his surgery. The International scientific community was
shocked to hear of Dr. Xiao’s arrest. Those of us who know Dr. Xiao well find it
difficult to believe that he is involved in these attacks.
Dr. Xiao is a compassionate man who is respected worldwide for his integrity and his
innovative scientific contributions to society. We implore the Chinese government
and authorities to treat Dr. Xiao fairly and to protect his human rights as these
charges are investigated. Please strongly consider Dr. Xiao’s scientific and
humanitarian contributions to the world as facts are gathered in this case.
Sincerely,
Kenneth M. Peters, MD
Professor and Chairman of Urology
Beaumont Hospital
Royal Oak, Michigan USA
Jack S. Elder, M.D.
Chief of Urology, Henry Ford Health System
Associate Director, Vattikuti Urology Institute
Department of Urology,
Children's Hospital of Michigan
Detroit, MI USA
Edwin A. Smith M.D.
Assistant Clinical Professor of Urology
Emory University School of Medicine
Atlanta, Georgia USA
Kevin M. Feber, MD, FAAP
Beaumont Children's Hospital
Royal Oak, MI USA
Ananias C. Diokno, M.D., F.A.C.S.
Executive Vice President & CMO
Beaumont Hospital
Royal Oak, Michigan 48073 USA
Juan José de Benito
Urologist
Hospital Nacional de Clínicas
Córdoba, Argentina.
William E. Nantau B.Sc., CNIM
Clinical Manager
Clinical Neurophysiology Department
Beaumont Hospital Royal Oak, MI USA
Evan J Kass MD,FACS,FAAP
Chief, Division of Pediatric Urology
Beaumont Childrens Hospital
Professor of Urology, Oakland University-William
Beaumont School of Medicine
USA
Jacques Corcos MD.
Professor of Urology, McGill University
General Secretary of the International Continence
Society
Jewish General hospital
3755 Cote Ste-Catherine
Montreal, Quebec, Canada H3T 1E2
Jose Gonzalez, M.D.
Department of Urology
Beaumont Hospital
Royal Oak, Michigan USA
Christopher Payne, MD
Associate Professor of Urology
Stanford University Medical School
Stanford, CA 94305-5118 USA
Kenneth I. Glassberg, MD
Director, Division of Pediatric Urology
Morgan Stanley Children's Hospital of New York-
Presbyterian
Professor of Urology, Columbia University
College of Physicians and Surgeons
3959 Broadway, CHN 1118 NY USA
Earl Y. Cheng, MD
Associate Professor of Urology
Children’s Memorial Hospital
Chicago, Illinois USA
Professor of Surgery
Senior Associate Scientist
Director of Urology Research
Divisions of Urology and
Developmental & Stem Cell Biology
The Hospital For Sick Children
Institute of Medical Science
University of Toronto
Henri B. LOTTMANN, MD, FEBU, FEBPS,
FRCS(england) FEBPU
Paediatric urology unit
Hopital Necker-Enfants-Malades
149, rue de Sèvres
75015 Paris, France
Dr. Amrish Vaidya MS. MCh.
Consultant Paediatric Surgeon,
Kokilaben Dhirubhai Ambani Hospital,
4 Bungalows, Andheri W, Mumbai, India
Marc Cendron, MD
Associate Professor in Urology
Harvard Medical School
Children’s Hospital Boston
Boston, MA USA
Stuart B. Bauer, MD
Associate Director, Neurourology
Professor of Urology
Harvard Medical School
Children’s Hospital Boston
Boston, MA USA
Edmond T. Gonzales, Jr., MD
Professor of Urology
Baylor College of Medicine
Houston TX USA
Richard Macchia, MD FACS
SUNY Distinguished Teaching Professor
Cleveland Clinic, Florida
Benjamin Girdler, MD
Urology Center of the Rockies
Fort Collins, Colorado USA
William C. de Groat, Ph.D.
Professor of Pharmacology
University of Pittsburgh
Pittsburgh, PA USA
Michael R. Ruggieri, Sr., Ph.D.
Director of Urologic Research
Temple University School of Medicine
Philadelphia, PA USA
Stanley J Kogan MD
Chief, Pediatric Urology
Children's Hospital at Montefiore
Bronx NY USA
Anthony Caldamone, MD
University Urologic Associates, Inc.
2 Dudley St Ste 185
Providence, RI 02905 USA
Yves Homsy MD, FRCSC, FAAP
Clinical Professor of Urological Surgery and
Pediatrics
University of South Florida
Children's Urology Group
5507 E. Longboat Blvd
Tampa FL 33615 USA
Dr. Enrique Turina
Professor of urology of the National University of
Buenos Aires
Chief of section Urology of Instituto de
Rehabilitación
Government of Buenos Aires, Argentina.
Dr. Angel Ozón
Urologist of the Instituto de Rehabilitación of Buenos
Aires
Dr. Daniel Ekizian
Urologist of Instituto de Rehabilitación.
Professor Dr. med. Karl-Dietrich Sievert
Vice Chair
Prof. of Urology, Director - Uro-oncology,
Neurourology, Incontinence, & Reconstructive
Urology
Department of Urology University of Tuebingen
D72076 Tuebingen, Germany
Holly Gilmer, MD
Chief of Pediatric Neurosurgery
Beaumont Hospital
Royal Oak, Michigan USA
Yegappan Lakshmanan, MD
Chief, Pediatric Urology
Children’s Hospital of Michigan
Detroit, MI USA
国际学术同仁声援肖传国医生的公开信
2010年9月29日
致所有人：
我们都有幸认识肖传国大夫多年。他是一位受国际学术界尊敬的外科医生和科学家，在恢复（脊椎损伤病人的）排尿和排便功能的神经再生研究中，他取得了重大进展。肖传国医生在美国完成了开创性的动物实验研究，阐明支配大腿的运动神经可以用来绕接支配膀胱和排便。这个绕接可以形成一个反射作用（反射弧）来启动来膀胱功能。他研究的成果已经多次发表在同行评议的国际科学期刊上。其他的科学家也已经重复并证实了肖医生的这些研究结果。
肖医生最终鼓起勇气将动物实验研究的成果转化到临床试验上，在中国的脊柱损伤和脊柱裂病人身上开展神经绕接（神经通路重建，即反射弧）手术。在中国，由于缺乏抗痉挛药物antimuscarinics和间歇性导尿术（自插导尿管），神经性膀胱功能障碍成为一种威胁生命的疾病。能缓解神经性膀胱功能障碍的并发症的疗法，就是一种能够拯救生命的成功。神经性膀胱和排大便功能障碍患者的病情是很痛苦的，包括遭受尿潴留、尿失禁、反复感染、肾功能不全、大便失禁、便秘等，生活质量极差。神经通路重建手术是一个非常复杂的手术，需要神经的再生。不应当把手术的成功定义为完全恢复排便排尿功能。这项手术的重点在于收益超过风险。
肖医生的临床研究成果发表在多种学术刊物上，并两次获得Jack Lapides佳作奖，这是奖励在神经泌尿科学界作出重要贡献的科学家的最崇高的国际性大奖之一。2008年，因为他的科学成就，肖医生还获得了国际儿童排尿节制学会颁发的Kelm Hjalmas演讲者（受邀做大会主题发言）荣誉。我们当中的许多人都曾经到中国去检视肖医生治疗过的患者的情况，观摩或者学习他发明的神经通路重建手术。肖医生是一位非常有经验的外科医生，他对患者热情照顾，不知疲倦地培训来自世界各地的医生们，来推广他的神经通路重建手术。
在美国，已经开展过一项独立而且严格的先期试验来检验这项手术的安全性和效益。术后一年的治疗结果最近发表在《泌尿科学杂志》（ Journal of Urology）上。在12个月的随访期间，在9位脊髓裂患者中，有7位患者，观察到皮下至膀胱的神经反射弧的构建成立，证明神经通路重建手术的确起了作用。这个成绩是了不起的，肖医生应该得到嘉奖。并且，一部分患者已经展现出大小便排便功能的改善，并将随时间推移而变得更好。术后36个月的成果正在分析中，不久就会发表。该先期试验的数据是支持“肖氏手术”的，现在受NIH（美国国立卫生研究院）资助的临床试验正在开展，以进一步在脊髓裂患者中研究腰椎至骶神经通路重建。还有，在肖医生的帮助和指导下，类似的临床试验也在世界范围内开展。
中国人民和政府应该为肖医生对病人所作出的贡献、对他的科学成就，和他在世界上培训医生以推广这项手术的诚意而自豪。国际科学界对肖医生被拘捕的消息感到震惊。我们这些了解肖医生的人，都对他涉入此案感到难以置信。
肖医生是一个极富同情心的绅士，他的诚实和对本学科作出的开创性的科学成就广受世界同行的尊敬。我们恳请中国政府和有关权威机构公正对待肖大夫，并在案情调查期间保障他的基本人权。在此事件中，请重视肖大夫对世界所作出的科学和人道主义事业的贡献。
谨致
Kenneth M. Peters, MD
Professor and Chairman of Urology
Beaumont Hospital
Royal Oak, Michigan
（美国Beaumont医院泌尿科主任）
Jack S. Elder, M.D.
Chief of Urology, Henry Ford Health System
Associate Director, Vattikuti Urology Institute
Department of Urology, Children's Hospital of Michigan
Clinical Professor of Urology, Case School of Medicine
(美国密西根儿童医院泌尿科主任)
Edwin A. Smith M.D.
Assistant Clinical Professor of Urology
Emory University School of Medicine
Atlanta, Georgia
（美国艾默里大学医学院临床助理教授）
Kevin M. Feber, MD, FAAP
Board Certified in Pediatric Urology
Comprehensive Urology
William Beaumont Children's Hospital
（美国William Beaumont儿童医院医生）
Ananias C. Diokno, M.D., F.A.C.S.Executive Vice President & CMOBeaumont HospitalRoyal Oak, Michigan 48073 USA
（美国Beaumont医院执行副总裁）
Juan José de Benito
Urologist
Hospital Nacional de Clínicas
Córdoba, Argentina.
（阿根廷国立医院）
William E. Nantau B.Sc., CNIMClinical ManagerClinical Neurophysiology DepartmentBeaumont Hospital Royal Oak
（美国Beaumont医院临床神经生理科临床主管）
Evan J Kass MD,FACS,FAAPChief, Division of Pediatric UrologyBeaumont Childrens HospitalProfessor of Urology, Oakland University-William Beaumont School of Medicine
（美国Beaumont儿童医院泌尿科主任，奥克兰大学医学院教授）
Jacques Corcos MD.Professor of Urology, McGill UniversityGeneral Secretary of the International Continence SocietyJewish General hospital3755 Cote Ste-CatherineMontreal, Quebec, Canada H3T 1E2
（加拿大麦基尔大学泌尿学教授，国际儿童排尿节制学会秘书长）
Jose Gonzalez, M.D.
Department of Urology
Beaumont Hospital
Royal Oak, Michigan
（美国Beaumont医院泌尿科医生）
Christopher Payne, MD
Associate Professor of Urology
Stanford University Medical School
Stanford, CA 94305-5118
（美国斯坦福大学医学院泌尿学副教授）
Kenneth I. Glassberg, MD
Director, Division of Pediatric Urology
Morgan Stanley Children's Hospital of New York-Presbyterian
Professor of Urology, Columbia University
College of Physicians and Surgeons
3959 Broadway, CHN 1118
（美国哥伦比亚大学医学院泌尿学教授，儿童泌尿学分科主任）
Earl Y. Cheng, MD
Associate Professor of Urology
Children’s Memorial Hospital
Chicago, Illinois
（美国芝加哥儿童医院泌尿学副教授）
Darius J. Bagli, MDCM
Professor of Surgery
Senior Associate Scientist
Director of Urology Research
Divisions of Urology and
Developmental & Stem Cell Biology
The Hospital For Sick Children
Institute of Medical Science
University of Toronto
（加拿大多伦多大学外科学教授，泌尿学研究主任）
Henri B. LOTTMANN, MD, FEBU, FEBPS, FRCS(england) FEBPU
Paediatric urology unit
Hopital Necker-Enfants-Malades
149, rue de Sèvres
75015 Paris
France
（法国Necker-Enfants-Malades医院儿童泌尿科医生）
Dr. Amrish Vaidya MS. MCh.Consultant Paediatric Surgeon,Kokilaben Dhirubhai Ambani Hospital,4 Bungalows, Andheri W, Mumbai, India
（印度Kokilaben Dhirubhai Ambani医院医生）
Marc Cendron, MD
Associate Professor in Urology
Harvard Medical School
Children’s Hospital Boston
Boston, MA
（美国哈佛大学医学院泌尿学副教授）
Stuart B. Bauer, MD
Associate Director, Neurourology
Professor of Urology
Harvard Medical School
Children’s Hospital Boston
Boston, MA
（美国哈佛大学医学院泌尿学教授，波士顿儿童医院神经泌尿科副主任）
Edmond T. Gonzales, Jr., MD
Professor of Urology
Baylor College of Medicine
（美国贝勒医学院泌尿学教授）
Richard Macchia, MD FACS
SUNY Distinguished Teaching Professor
Cleveland Clinic, Florida
（美国Cleveland临床中心教授）
Benjamin Girdler, MD
Urology Center of the Rockies
Fort Collins, Colorado
（美国科罗拉多洛基泌尿中心医生）
William C. de Groat, Ph.D.
Professor of Pharmacology
University of Pittsburgh
（美国匹兹堡大学药理学教授）
Michael R. Ruggieri, Sr., Ph.D.
Director of Urologic Research
Temple University School of Medicine
（美国坦普大学医学院泌尿学研究主任）
Stanley J Kogan MDChief, Pediatric UrologyChildren's Hospital at MontefioreBronx NY USA
（美国Montefiore儿童医院儿童泌尿科主任）
Anthony Caldamone, MD
University Urologic Associates, Inc.2 Dudley St Ste 185Providence, RI 02905
（美国布朗大学泌尿学中心医生）
Yves Homsy MD, FRCSC, FAAP Clinical Professor of Urological Surgery and Pediatrics University of South Florida Children's Urology Group 5507 E. Longboat Blvd Tampa FL 33615
（美国南弗罗里达大学临床泌尿学教授）
Dr. Enrique Turina
Professor of urology of the National University of Buenos Aires
Chief of section Urology of Instituto de Rehabilitación
Government of Buenos Aires, Argentina.
（阿根廷国立Buenos Aires大学泌尿学教授）
Dr. Angel Ozón
Urologist of the Instituto de Rehabilitación of Buenos Aires
（阿根廷国立Buenos Aires大学泌尿学医生）
Dr. Daniel Ekizian
Urologist of Instituto de Rehabilitación.
（阿根廷国立Buenos Aires大学泌尿学医生）
Professor Dr. med. Karl-Dietrich Sievert
Vice Chair Prof. of Urology, Director - Uro-oncology, Neurourology, Incontinence, & Reconstructive Urology Department of Urology University of Tuebingen D72076 Tuebingen, Germany
（德国Tuebingen大学泌尿学教授、主任）
Holly Gilmer, MD
Chief of Pediatric Neurosurgery
Beaumont Hospital
Royal Oak, Michigan
（美国Beaumont医院儿童神经外科主任）
Yegappan Lakshmanan, MD
Chief, Pediatric Urology
Children’s Hospital of Michigan
（美国密西根儿童医院儿童泌尿科主任）
链接出处
http://www.here4news.com/article/3097808